Quarterly report pursuant to Section 13 or 15(d)

Offerings of Common Stock and Warrants - Warrants - General Information (Details)

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Offerings of Common Stock and Warrants - Warrants - General Information (Details)
1 Months Ended 9 Months Ended
Oct. 01, 2020
USD ($)
$ / shares
shares
Jun. 16, 2020
USD ($)
$ / shares
Dec. 09, 2019
USD ($)
$ / shares
Oct. 24, 2019
$ / shares
shares
Sep. 04, 2019
$ / shares
shares
Feb. 04, 2019
USD ($)
$ / shares
shares
Jan. 31, 2021
item
$ / shares
shares
Dec. 31, 2020
USD ($)
Dec. 31, 2021
USD ($)
shares
Warrants                  
Deemed dividend | $               $ 15,000  
Goldman Warrant, Purchase Warrant for Common Shares                  
Warrants                  
Issued warrants (in shares)           1      
Exercise price (in dollars per share) | $ / shares   $ 2.61 $ 3.80     $ 8.86      
Aggregate shares called by warrants (in shares)           404,634     463,067
Aggregate shares called by each warrant (in shares)           404,634      
Purchase price of warrants | $           $ 150,000      
Date from which warrants exercisable           Aug. 04, 2019      
Maturity date           Feb. 04, 2024      
Expected proceeds from warrants | $   $ 1,186,313              
Amortization of debt discount (additional debt discount) | $   $ (100,000) $ (300,000)            
Value of warrants | $                 $ 2,300,000
Goldman 2020 Warrant, Purchase Warrant for Common Shares                  
Warrants                  
Issued warrants (in shares) 1                
Exercise price (in dollars per share) | $ / shares $ 4.76                
Aggregate shares called by warrants (in shares) 291,295                
Aggregate shares called by each warrant (in shares) 291,295                
Date from which warrants exercisable Oct. 01, 2020                
Maturity date Feb. 04, 2024                
Private placement, purchase price | $ $ 10,000                
Value of warrants | $ $ 800,000                
September 2019 Pre-Funded Common Stock Warrants                  
Warrants                  
Exercise price (in dollars per share) | $ / shares       $ 0.001          
Aggregate shares called by warrants (in shares)         440,000        
Purchase price per warrant (in dollars per share) | $ / shares         $ 5.00        
Warrants exercised (in shares)       440,000          
September 2019 Series D Common Stock Warrants                  
Warrants                  
Outstanding warrants (in shares)                 75,000
Exercise price (in dollars per share) | $ / shares         $ 6.12   $ 6.12    
Aggregate shares called by warrants (in shares)         765,000        
Term         5 years        
Date from which warrants exercisable         Apr. 02, 2020        
Maturity date         Apr. 02, 2025        
Shares as percentage of Registered Direct Offering (as a percent)         75.00%        
Number of warrant holders | item             3    
Warrants exercised (in shares)             690,000    
Warrants exercised, shares issued (in shares)             352,279