Quarterly report pursuant to Section 13 or 15(d)

Offerings of Common Stock and Warrants and At-the-Market Offering Program - Warrants - General Information (Details)

Offerings of Common Stock and Warrants and At-the-Market Offering Program - Warrants - General Information (Details) - USD ($)							1 Months Ended		9 Months Ended
	Oct. 01, 2020	Jun. 16, 2020	Dec. 09, 2019	Oct. 24, 2019	Sep. 04, 2019	Feb. 04, 2019	Oct. 31, 2016	Apr. 30, 2016	Dec. 31, 2020	Dec. 31, 2019
Warrants
Deemed dividend									$ 15,000	$ 75,000
Series A Common Stock Warrants
Warrants
Outstanding warrants (in shares)									271,875
Series A Common Stock Warrants, Expiring 25 October 2021
Warrants
Issued warrants (in shares)								217,875
Exercise price (in dollars per share)								$ 25.50
Maturity date								Oct. 25, 2021
Series A Common Stock Warrants, Expiring 22 April 2021
Warrants
Issued warrants (in shares)							54,000
Exercise price (in dollars per share)							$ 13.40		$ 1.15
Maturity date							Apr. 22, 2021
Goldman Warrant, Purchase Warrant for Common Shares
Warrants
Issued warrants (in shares)						1			8,542
Exercise price (in dollars per share)		$ 2.61	$ 3.80			$ 8.86
Aggregate shares called by warrants (in shares)						404,634			463,067
Aggregate shares called by each warrant (in shares)						404,634
Purchase price of warrants						$ 150,000
Date from which warrants exercisable						Aug. 04, 2019
Maturity date						Feb. 04, 2024
Deemed dividend									$ 15,000
Expected proceeds from warrants		$ 1,186,313
Amortization of debt discount (additional debt discount)		$ (100,000)	$ (300,000)
Value of warrants									$ 2,300,000
Goldman 2020 Warrant, Purchase Warrant for Common Shares
Warrants
Issued warrants (in shares)	1
Exercise price (in dollars per share)	$ 4.76
Aggregate shares called by warrants (in shares)	291,295
Aggregate shares called by each warrant (in shares)	291,295
Date from which warrants exercisable	Oct. 01, 2020
Maturity date	Feb. 04, 2024
Private placement, purchase price	$ 10,000
Value of warrants	$ 800,000
September 2019 Pre-Funded Common Stock Warrants
Warrants
Exercise price (in dollars per share)				$ 0.001
Aggregate shares called by warrants (in shares)					440,000
Purchase price per warrant (in dollars per share)					$ 5.00
Warrants exercised (in shares)				440,000
September 2019 Series D Common Stock Warrants
Warrants
Exercise price (in dollars per share)					$ 6.12
Aggregate shares called by warrants (in shares)					765,000
Term					5 years
Date from which warrants exercisable					Apr. 02, 2020
Maturity date					Apr. 02, 2025
Shares as percentage of Registered Direct Offering (as a percent)					75.00%
Warrants exercised, cumulative (in shares)									312,020